Identifiers: city · village · CDP · town
| Rank | Community | Population |
|---|---|---|
| 1 | Cape Girardeau (city), MO | 39,540 |
| 2 | Jackson (city), MO | 15,481 |
| 3 | Scott City (city), MO | 4,346 |
| 4 | Chaffee (city), MO | 3,057 |
| 5 | Oran (city), MO | 1,195 |
| 6 | Miner (city), MO | 916 |
| 7 | Benton (city), MO | 866 |
| 8 | Morley (city), MO | 630 |
| 9 | Gordonville (village), MO | 625 |
| 10 | Kelso (village), MO | 554 |
| 11 | Delta (city), MO | 376 |
| 12 | Millersville (CDP), MO | 240 |
| 13 | Oak Ridge (town), MO | 237 |
| 14 | New Hamburg (CDP), MO | 218 |
| 15 | Blodgett (city), MO | 209 |
| 16 | Dutchtown (CDP), MO | 163 |
| 17 | Shawneetown (CDP), MO | 132 |
| 18 | Pocahontas (town), MO | 97 |
| 19 | Allenville (village), MO | 95 |
| 20 | Whitewater (town), MO | 88 |
Identifiers: city · village · CDP · town
| Rank | Community | Population |
|---|---|---|
| 1 | Cape Girardeau (city), MO | 39,540 |
| 2 | Jackson (city), MO | 15,481 |
| 3 | Scott City (city), MO | 4,346 |
| 4 | Chaffee (city), MO | 3,057 |
| 5 | Oran (city), MO | 1,195 |
| 6 | Miner (city), MO | 916 |
| 7 | Benton (city), MO | 866 |
| 8 | Morley (city), MO | 630 |
| 9 | Gordonville (village), MO | 625 |
| 10 | Kelso (village), MO | 554 |
| 11 | Delta (city), MO | 376 |
| 12 | Millersville (CDP), MO | 240 |
| 13 | Oak Ridge (town), MO | 237 |
| 14 | New Hamburg (CDP), MO | 218 |
| 15 | Blodgett (city), MO | 209 |
| 16 | Dutchtown (CDP), MO | 163 |
| 17 | Shawneetown (CDP), MO | 132 |
| 18 | Pocahontas (town), MO | 97 |
| 19 | Allenville (village), MO | 95 |
| 20 | Whitewater (town), MO | 88 |