Identifiers: city · CDP
| Rank | Community | Population |
|---|---|---|
| 1 | St. Louis (city), MO | 301,578 |
| 2 | Chesterfield (city), MO | 49,999 |
| 3 | Oakville (CDP), MO | 36,301 |
| 4 | Wildwood (city), MO | 35,417 |
| 5 | University City (city), MO | 35,065 |
| 6 | Ballwin (city), MO | 31,103 |
| 7 | Kirkwood (city), MO | 29,461 |
| 8 | Mehlville (CDP), MO | 28,955 |
| 9 | Maryland Heights (city), MO | 28,284 |
| 10 | Webster Groves (city), MO | 24,010 |
| 11 | Arnold (city), MO | 20,858 |
| 12 | Affton (CDP), MO | 20,417 |
| 13 | Creve Coeur (city), MO | 18,834 |
| 14 | Manchester (city), MO | 18,333 |
| 15 | Concord (CDP), MO | 17,668 |
| 16 | Clayton (city), MO | 17,355 |
| 17 | Lemay (CDP), MO | 17,117 |
| 18 | Overland (city), MO | 15,955 |
| 19 | St. Ann (city), MO | 13,019 |
| 20 | Festus (city), MO | 12,706 |