Identifiers: city · CDP · village
| Rank | Community | Population |
|---|---|---|
| 1 | Portsmouth (city), OH | 18,252 |
| 2 | Ironton (city), OH | 10,571 |
| 3 | Wheelersburg (CDP), OH | 6,531 |
| 4 | Waverly (village), OH | 4,165 |
| 5 | West Portsmouth (CDP), OH | 2,928 |
| 6 | New Boston (village), OH | 2,297 |
| 7 | Rosemount (CDP), OH | 2,117 |
| 8 | Piketon (village), OH | 2,111 |
| 9 | Lucasville (CDP), OH | 1,655 |
| 10 | Franklin Furnace (CDP), OH | 1,525 |
| 11 | Sciotodale (CDP), OH | 1,049 |
| 12 | Clarktown (CDP), OH | 911 |
| 13 | South Webster (village), OH | 670 |
| 14 | Minford (CDP), OH | 641 |
| 15 | Friendship (CDP), OH | 343 |
| 16 | McDermott (CDP), OH | 308 |
| 17 | Hanging Rock (village), OH | 204 |
| 18 | Stockdale (CDP), OH | 111 |