Identifiers: city · CDP
| Rank | Community | Population |
|---|---|---|
| 1 | Hermiston (city), OR | 19,354 |
| 2 | Pendleton (city), OR | 17,107 |
| 3 | Stanfield (city), OR | 2,144 |
| 4 | Pilot Rock (city), OR | 1,328 |
| 5 | Athena (city), OR | 1,209 |
| 6 | Mission (CDP), OR | 960 |
| 7 | Green Meadows (CDP), OR | 675 |
| 8 | Echo (city), OR | 632 |
| 9 | Tutuilla (CDP), OR | 448 |
| 10 | Adams (city), OR | 389 |
| 11 | Gopher Flats (CDP), OR | 329 |
| 12 | Riverside (CDP), OR | 213 |
| 13 | Helix (city), OR | 194 |
| 14 | Kirkpatrick (CDP), OR | 160 |
| 15 | Meacham (CDP), OR | 85 |
| 16 | Cayuse (CDP), OR | 66 |