Identifiers: city · CDP
| Rank | Community | Population |
|---|---|---|
| 1 | Medford (city), OR | 85,824 |
| 2 | Ashland (city), OR | 21,360 |
| 3 | Central Point (city), OR | 18,997 |
| 4 | Eagle Point (city), OR | 9,686 |
| 5 | White City (CDP), OR | 9,090 |
| 6 | Talent (city), OR | 6,282 |
| 7 | Phoenix (city), OR | 4,475 |
| 8 | Shady Cove (city), OR | 3,081 |
| 9 | Jacksonville (city), OR | 3,020 |
| 10 | Rogue River (city), OR | 2,407 |
| 11 | Gold Hill (city), OR | 1,335 |
| 12 | Foots Creek (CDP), OR | 734 |