Identifiers: city · town · CDP
| Rank | Community | Population |
|---|---|---|
| 1 | Marion (city), SC | 6,448 |
| 2 | Dillon (city), SC | 6,384 |
| 3 | Mullins (city), SC | 4,026 |
| 4 | McColl (town), SC | 2,070 |
| 5 | Latta (town), SC | 1,296 |
| 6 | Quinby (town), SC | 915 |
| 7 | Hamer (CDP), SC | 820 |
| 8 | Newtown (CDP), SC | 770 |
| 9 | Lake View (town), SC | 764 |
| 10 | Little Rock (CDP), SC | 658 |
| 11 | Clio (town), SC | 608 |
| 12 | Floydale (CDP), SC | 421 |
| 13 | Nichols (town), SC | 234 |
| 14 | Sellers (town), SC | 147 |
| 15 | Zion (CDP), SC | 136 |