Identifiers: city · town · CDP
| Rank | Community | Population |
|---|---|---|
| 1 | Charleston (city), SC | 150,227 |
| 2 | North Charleston (city), SC | 114,852 |
| 3 | Mount Pleasant (town), SC | 90,801 |
| 4 | Summerville (town), SC | 50,915 |
| 5 | Goose Creek (city), SC | 45,946 |
| 6 | Hanahan (city), SC | 20,325 |
| 7 | Ladson (CDP), SC | 15,550 |
| 8 | Moncks Corner (town), SC | 13,297 |
| 9 | Sangaree (CDP), SC | 7,781 |
| 10 | Ridgeville (town), SC | 1,672 |
| 11 | Pimlico (CDP), SC | 1,208 |
| 12 | Lincolnville (town), SC | 1,147 |
| 13 | Pinopolis (CDP), SC | 982 |