Identifiers: city · town · CDP
| Rank | Community | Population |
|---|---|---|
| 1 | Mitchell (city), SD | 15,660 |
| 2 | Alexandria (city), SD | 649 |
| 3 | Mount Vernon (city), SD | 461 |
| 4 | Ethan (town), SD | 365 |
| 5 | Upland Colony (CDP), SD | 178 |
| 6 | Letcher (town), SD | 159 |
| 7 | Artesian (town), SD | 129 |
| 8 | Forestburg (CDP), SD | 54 |
| 9 | Loomis (CDP), SD | 33 |
Identifiers: city · town · CDP
| Rank | Community | Population |
|---|---|---|
| 1 | Mitchell (city), SD | 15,660 |
| 2 | Parkston (city), SD | 1,567 |
| 3 | Plankinton (city), SD | 781 |
| 4 | Alexandria (city), SD | 649 |
| 5 | Emery (city), SD | 484 |
| 6 | Mount Vernon (city), SD | 461 |
| 7 | Ethan (town), SD | 365 |
| 8 | Stickney (town), SD | 321 |
| 9 | Dimock (town), SD | 137 |
| 10 | Spencer (city), SD | 136 |
| 11 | Millbrook Colony (CDP), SD | 98 |
| 12 | Fulton (town), SD | 87 |
| 13 | Rockport Colony (CDP), SD | 77 |
| 14 | Loomis (CDP), SD | 33 |
| 15 | Farmer (town), SD | 15 |
| 16 | Rosedale Colony (CDP), SD | 0 |