Identifiers: city · CDP
| Rank | Community | Population |
|---|---|---|
| 1 | McAllen (city), TX | 142,210 |
| 2 | Edinburg (city), TX | 100,243 |
| 3 | Mission (city), TX | 85,778 |
| 4 | Pharr (city), TX | 79,715 |
| 5 | Weslaco (city), TX | 40,160 |
| 6 | San Juan (city), TX | 35,294 |
| 7 | Alamo (city), TX | 19,493 |
| 8 | Alton (city), TX | 18,198 |
| 9 | Donna (city), TX | 16,797 |
| 10 | Mercedes (city), TX | 16,258 |
| 11 | Palmview (city), TX | 15,830 |
| 12 | Hidalgo (city), TX | 13,964 |
| 13 | La Homa (CDP), TX | 11,267 |
| 14 | Murillo (CDP), TX | 9,158 |
| 15 | La Feria (city), TX | 6,817 |
| 16 | Penitas (city), TX | 6,460 |
| 17 | Mila Doce (CDP), TX | 6,162 |
| 18 | Elsa (city), TX | 5,668 |
| 19 | Doffing (CDP), TX | 5,618 |
| 20 | Progreso (city), TX | 4,807 |