Identifiers: city · CDP · town
| Rank | Community | Population |
|---|---|---|
| 1 | Roanoke (city), VA | 100,011 |
| 2 | Cave Spring (CDP), VA | 26,755 |
| 3 | Salem (city), VA | 25,346 |
| 4 | Hollins (CDP), VA | 15,574 |
| 5 | Vinton (town), VA | 8,059 |
| 6 | Cloverdale (CDP), VA | 3,410 |
| 7 | Blue Ridge (CDP), VA | 3,185 |
| 8 | Daleville (CDP), VA | 3,070 |
| 9 | Laymantown (CDP), VA | 1,867 |
| 10 | Shawsville (CDP), VA | 1,241 |
| 11 | Buchanan (town), VA | 1,196 |
| 12 | Glenvar (CDP), VA | 892 |
| 13 | Elliston (CDP), VA | 855 |
| 14 | Fincastle (town), VA | 755 |
| 15 | Montvale (CDP), VA | 635 |
| 16 | Stewartsville (CDP), VA | 533 |
| 17 | Troutville (town), VA | 458 |
| 18 | Lafayette (CDP), VA | 429 |
| 19 | Boones Mill (town), VA | 259 |